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68 years old, female; cT4(levator ani muscle)N1(multiple perirectal nodes) squamous cell carcinoma of the anal canal; treatment: definitive chemoradiation.
26 years old, male; cT4b (aorta, diaphragm, pancreatic body) N0 of the cardias; treatment: neoadjuvant chemoradiation (involved-field).
66 years old, female; cT4b(hypopharynx)N2 (4-5 enlarged para-tracheal and para-esophageal nodes) squamous cell carcinoma of the cervical esophagus; treatment: definitive chemoradiation.
75 years old, male; cT4(vessels) N0 adenocarcinoma of the pancreatic head treated with multiple drug chemotherapy (partial response); treatment: neoadjuvant involved-field chemoradiation.
44 years old, female; pT3N1R1 pancreatic adenocarcinoma; treatment: postoperative radiotherapy after Whipple resection.
52 years old, male; cT4b(prostate)N1b(3 enlarged nodes) of the lower rectum; treatment: preoperative chemoradiation.